SH2B2 wt Allele

Preferred Label : SH2B2 wt Allele;

NCIt synonyms : Adaptor Protein with Pleckstrin Homology and SRC Homology 2 Domains Gene; SH2B Adaptor Protein 2 wt Allele; APS; APS wt Allele;

NCIt definition : Human SH2B2 wild-type allele is located in the vicinity of 7q22 and is approximately 34 kb in length. This allele, which encodes SH2B adapter protein 2, plays a role in the modulation of both insulin and B-cell antigen-dependent signaling pathways.;

GenBank Accession Number : NM_020979;

Details

Origin ID

C52368;

UMLS CUI

C1706670;

Automatic exact mappings (from CISMeF team)
- Antiphospholipid syndrome [ORDO Disease]
- Autoimmune polyendocrinopathy [ORDO Disease]
- Autoimmune polyendocrinopathy (disorder) [SNOMED CT concept]
- Kallikrein-related peptidase 3 [OMIM gene]
- Sh2b adaptor protein 2 [OMIM gene]
- anterior parolfactory sulcus [UBERON concept]
- surgical flaps [MeSH Descriptor]
OMIM relation
- Sh2b adaptor protein 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 101521887-101555613 [NCIt concept]
gene_in_chromosomal_location
- 7q22 [NCIt concept]
gene_is_element_in_pathway
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- B-Cell Activation [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]

Keyword's position in hierarchy(ies) :

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