CYP3A7 wt Allele

Preferred Label : CYP3A7 wt Allele;

NCIt synonyms : Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 wt Allele;

NCIt definition : Human CYP3A7 wild-type allele is located within 7q21-q22.1 and is approximately 30 kb in length. This allele, which encodes cytochrome P450 3A7 protein, plays a role in the hydroxylation of testosterone and dehydroepiandrosterone 3-sulfate. It is also involved in the oxidation of drugs and xenobiotics.;

GenBank Accession Number : NM_000765;

Details

Origin ID

C52365;

UMLS CUI

C1707240;

OMIM relation
- Cytochrome p450, subfamily iiia, polypeptide 7 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 7q21-q22.1 [NCIt concept]
gene_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- Linoleic Acid Metabolism Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_plays_role_in_process
- Detoxification [NCIt concept]
- Drug Metabolism [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Iron Chelation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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