IGFBP6 wt Allele

Preferred Label : IGFBP6 wt Allele;

NCIt synonyms : IBP6; Insulin-Like Growth Factor Binding Protein 6 wt Allele; IBP-6; IGFBP-6;

NCIt definition : Human IGFBP6 wild-type allele is located within 12q13 and is approximately 5 kb in length. This allele, which encodes insulin-like growth factor-binding protein 6, is involved in the regulation of insulin-like growth factor interactions, cellular proliferation and apoptosis.;

NCIt note : Acts as a cell density and Ca 2 dependent inhibitor of cell growth.;

GenBank Accession Number : NM_002178;

Details

Origin ID

C52286;

UMLS CUI

C1705345;

Automatic exact mappings (from CISMeF team)
- 2-phenyl-5,5-dimethyltetrahydro-1,4-oxazine [MeSH Supplementary Concept]
- Insulin-Like growth factor binding protein 6 [MeSH concept]
- Insulin-Like growth factor binding protein 6 [MeSH Descriptor]
- Insulin-like growth factor-binding protein 6 [OMIM gene]
- ciliary neurotrophic factor receptor activity [GO term]
- interleukin-11 receptor activity [GO term]
- interleukin-6 receptor activity [GO term]
- leucine rich pentatricopeptide repeat containing [ORDO Gene]
Currated CISMeF NLP mapping
- obsolete gp130 [GO term]
OMIM relation
- Insulin-like growth factor-binding protein 6 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 12: 51777716-51782391 [NCIt concept]
gene_in_chromosomal_location
- 12q13 [NCIt concept]
gene_is_element_in_pathway
- Food Intake and Energy Homeostasis Pathway [NCIt concept]
gene_plays_role_in_process
- Inhibition of Cell Proliferation [NCIt concept]
- Intracellular Transport [NCIt concept]
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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