IGFBP1 wt Allele

Preferred Label : IGFBP1 wt Allele;

NCIt synonyms : IGFBP1; IGF-BP25; IBP1; Insulin-Like Growth Factor Binding Protein 1 wt Allele; hIGFBP-1; PP12; AFBP;

NCIt definition : Human IGFBP1 wild-type allele is located within 7p13-p12 and is approximately 5 kb in length. This allele, which encodes insulin-like growth factor-binding protein 1, plays a role in insulin-like growth factor regulation and interactions involving cell surface receptors.;

NCIt note : Hypoxia appears to upregulate IGFBP1 expression. IGFBP1 binds equally to plasma IGF I and IGF II with high affinity.;

GenBank Accession Number : NM_000596;

Details

Origin ID

C52280;

UMLS CUI

C1705677;

OMIM relation
- Insulin-like growth factor-binding protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 7: 45701327-45706499 [NCIt concept]
gene_in_chromosomal_location
- 7p13-p12 [NCIt concept]
gene_is_element_in_pathway
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
- Food Intake and Energy Homeostasis Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
gene_plays_role_in_process
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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