NCIt synonyms : Protein Receptor Tyrosine Kinase, Epithelial-Specific, TIE-2 Gene; TEK; VMCM1; TIE2; VMCM; TIE-2; TEK Tyrosine Kinase, Endothelial (Venous Malformations, Multiple Cutaneous and Mucosal)
Gene; CD202b; GLC3E; TEK Tyrosine Kinase, Endothelial Gene; TEK Receptor Tyrosine Kinase wt Allele;
NCIt definition : Human TEK wild-type allele is located within 9p21 and is approximately 121 kb in length.
This allele, which encodes angiopoietin-1 receptor protein, is involved in angiogenesis,
endothelial cell proliferation and differentiation and endothelial cell patterning
during vascular morphogenesis. Defects and deficiencies in TEK are associated with
venous malformations.;