SYK wt Allele - CISMeF

Preferred Label : SYK wt Allele;

NCIt synonyms : IMD82; SYK; Spleen Tyrosine Kinase wt Allele; p72-SYK;

NCIt definition : Human SYK wild-type allele is located within 9q22 and is approximately 94 kb in length. This allele, which encodes tyrosine-protein kinase SYK protein, plays a role in coupling activated immunoreceptors to signal transduction events that mediate diverse cellular responses, including proliferation, differentiation and phagocytosis.;

GenBank Accession Number : NM_003177;

Details

Origin ID

C52220;

UMLS CUI

C1706351;

Automatic exact mappings (from CISMeF team)
- Protein-tyrosine kinase syk [OMIM gene]
- sensilla [MeSH Descriptor]
- silk [MeSH Descriptor]
OMIM relation
- Protein-tyrosine kinase syk [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1q12-q23 [NCIt concept]
gene_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Aspirin Inhibition of Platelet Activation Pathway [NCIt concept]
- Atypical NF-kappaB Signaling Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- FAS Signaling Pathway PID [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Fc-Epsilon Receptor I Signaling Pathway PID [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Ras-Independent Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- B-Cell Activation [NCIt concept]
- Calcium Signaling [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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