" /> 18F-Fluoromisonidazole - CISMeF





Preferred Label : 18F-Fluoromisonidazole;

NCIt synonyms : 18F-Misonidazole; FMISO; 18F-MISO;

NCIt related terms : 18F-MISO; FLUOROMISONIDAZOLE F-18;

NCIt definition : A radiofluorinated 2-nitroimidazole derivate with hypoxia-specific tracer activity. Misonidazole is reduced under hypoxic conditions and in reduced form covalently binds to macromolecules in hypoxic cells. 18F (fluorine-18) radiofluorination of misonidazole to form 18F-fluoromisonidazole allows radioisotopic imaging of reduced misonidazole bound to macromolecules in hypoxic cells.;

Alternative definition : NCI-GLOSS: A radioactive substance being studied as an imaging agent in head and neck cancers and other types of cancer. It binds to large molecules in tumor cells that have a low level of oxygen. Radiation given off by 18F-fluoromisonidazole is detected by a PET scan. The amount of 18F-fluoromisonidazole in the tumor may help decide the best treatment and help predict whether the cancer will come back after treatment. 18F-fluoromisonidazole is a type of radioimaging agent.;

UNII : 8MSY49469G;

CAS number : 104613-87-8;

Codes from synonyms : CDR0000599988; CDR0000599959; CDR0000599987;

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07/05/2025


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