KDR wt Allele - CISMeF

Preferred Label : KDR wt Allele;

NCIt synonyms : FLK1; Kinase Insert Domain Receptor wt Allele; VEGFR2; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase) Gene; VEGFR; Tyrosine Kinase Growth Factor Receptor FLK1, Mouse, Homolog of Gene; CD309;

NCIt definition : Human KDR wild-type allele is located within 4q11-q12 and is approximately 47 kb in length. This allele, which encodes vascular endothelial growth factor receptor 2 protein, plays a role in vascular development, regulation of vascular permeability and VEGF signal transduction.;

GenBank Accession Number : NM_002253;

Details

Origin ID

C52172;

UMLS CUI

C1705712;

OMIM relation
- Kinase insert domain receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Hemangioma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 4: 55832690-55785577 [NCIt concept]
gene_in_chromosomal_location
- 4q11-q12 [NCIt concept]
gene_is_element_in_pathway
- Angiogenesis Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Angiogenic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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