STAT4 wt Allele

Preferred Label : STAT4 wt Allele;

NCIt synonyms : Signal Transducer and Activator of Transcription 4 wt Allele;

NCIt definition : Human STAT4 wild-type allele is located within 2q32.2-q32.3 and is approximately 122 kb in length. This allele, which encodes signal transducer and activator of transcription 4 protein, is involved in both the transcriptional activation of interleukin-12 responsive genes and T helper cell differentiation.;

GenBank Accession Number : NM_003151;

Détails

Origin ID

C52154;

UMLS CUI

C1710006;

OMIM relation
- Signal transducer and activator of transcription 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- Crohn Disease [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 2q32.2-q32.3 [NCIt concept]
gene_is_element_in_pathway
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
- IL27-Mediated Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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