" /> PHB1 wt Allele - CISMeF





Preferred Label : PHB1 wt Allele;

NCIt synonyms : Prohibitin Gene; HEL-215; HEL-S-54e; Prohibitin 1 wt Allele; PHB;

NCIt related terms : PHB wt Allele;

NCIt definition : Human PHB1 wild-type allele is located in the vicinity of 17q21.33 and is approximately 11 kb in length. This allele, which encodes prohibitin 1 protein, plays a role in the repression of cellular proliferation. Mutations in this gene have been linked to sporadic breast cancer.;

NCIt note : The PHB gene is expressed as two transcripts with varying lengths of 3-prime UTR. The longer transcript is present at higher levels in proliferating cells; the longer 3-prime UTR may act as a trans regulator. The human prohibitin family consists of one functional gene and four processed pseudogenes: PHBP1, PHBP2, PHBP3, and PHBP4.;

GenBank Accession Number : NM_002634;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.