" /> RSF1 wt Allele - CISMeF





Preferred Label : RSF1 wt Allele;

NCIt synonyms : HBXAP; RSF; RSF-1; XAP8; Remodeling and Spacing Factor 1 wt Allele; HBXAP wt Allele;

NCIt definition : Human RSF1 wild-type allele is located in the vicinity of 11q14.1 and is approximately 155 kb in length. This allele, which encodes remodeling and spacing factor 1 protein, plays a role in transcriptional repression, transcriptional co-activation and nucleosome assembly controlled by the RSF chromatin remodeling complex. The RSF1 gene is overexpressed in high-grade ovarian serous carcinoma.;

NCIt note : The RSF gene is a putative oncogene in ovarian cancer. This gene has been shown to be amplified in some high-grade ovarian carcinomas. Amplification or overexpression of the RSF gene in ovarian cancer is correlated with reduced length of patient survival.;

GenBank Accession Number : NM_016578;

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31/07/2025


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