HMGN3 wt Allele

Preferred Label : HMGN3 wt Allele;

NCIt synonyms : High-Mobility Group Nucleosomal Binding Domain 3 wt Allele; PNAS-24; TRIP7;

NCIt definition : Human HMGN3 wild-type allele is located in the vicinity of 6q14.1 and is approximately 33 kb in length. This allele, which encodes high mobility group nucleosome-binding domain-containing protein 3, plays a role in both thyroid receptor beta binding and modulation of chromatin modifications.;

NCIt note : The HMGN3 gene produces two mRNA transcripts via alternative splicing which, in turn, encode two distinct isoforms of high mobility group nucleosome-binding domain-containing protein 3. Binding of this protein to thyroid receptor beta is dependent on the presence of thyroid hormone.;

GenBank Accession Number : NM_004242;

Details

Origin ID

C52081;

UMLS CUI

C1706257;

OMIM relation
- High mobility group nucleosomal binding protein 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 6: 80001174-79967683 [NCIt concept]
gene_in_chromosomal_location
- 6q14.3 [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- DNA Binding [NCIt concept]
- Transcription [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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