" /> HMGN2 wt Allele - CISMeF





Preferred Label : HMGN2 wt Allele;

NCIt synonyms : High-Mobility Group Nucleosomal Binding Domain 2 wt Allele; MGC5629; HMG17;

NCIt definition : Human HMGN2 wild-type allele is located in the vicinity of 1p36.1 and is approximately 4 kb in length. This allele, which encodes nonhistone chromosomal protein HMG-17 protein, plays a role in the modulation of chromatin modifications.;

NCIt note : A fragment of nonhistone chromosomal protein HMG-17 protein has been shown to localize to the nuclei of tumor cells and tumor endothelial cells in vivo; therefore, this peptide could potentially be utilized for targeting cytotoxic drugs and gene therapy vectors into tumors. Antibodies to nonhistone chromosomal protein HMG-17 protein are found in patients with many different types of autoimmune rheumatic diseases; however, these antibodies are more frequently present in patients with systemic lupus erythematosus.;

GenBank Accession Number : NM_005517;

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31/07/2025


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