" /> DAB2 wt Allele - CISMeF





Preferred Label : DAB2 wt Allele;

NCIt synonyms : Disabled Homolog 2, Mitogen-Responsive Phosphoprotein (Drosophila) wt Allele; DOC-2; DOC2;

NCIt definition : Human DAB2 wild-type allele is located within 5p13 and is approximately 52 kb in length. This allele, which encodes disabled homolog 2 protein, plays a role in the inhibition of cell proliferation. Down-regulation or complete loss of DAB2 gene expression is associated with certain cancers such as breast cancer and ovarian epithelial carcinomas.;

NCIt note : The DAB2 gene produces two mRNA transcripts via alternative splicing which, in turn, encode distinct protein isoforms. This gene is a candidate tumor suppressor gene.;

GenBank Accession Number : NM_001343;

Détails


Vous pouvez consulter :


Nous contacter.
29/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.