SMARCC2 wt Allele

Preferred Label : SMARCC2 wt Allele;

NCIt synonyms : Mammalian Chromatin Remodeling Complex, BRG1-Associated Factor 170 Gene; SWI/SNF-Related, Matrix-Associated, Actin-Dependent Regulator of Chromatin, Subfamily C, Member 2 wt Allele; SWI/SNF Complex 170 kDa Subunit Gene; SWI3-Like Protein Gene; Chromatin Remodeling Complex BAF170 Subunit Gene; Mammalian Chromatin Remodeling Complex BRG1-Associated Factor 170 Gene; BRG1-Associated Factor, 170-kD Gene; CRACC2; SRG3; BAF170; Rsc8;

NCIt definition : Human SMARCC2 wild-type allele is located within 12q13-q14 and is approximately 26 kb in length. This allele, which encodes SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C, member 2 protein, plays a role in both transcriptional activation and chromosome conformation.;

NCIt note : The SMARCC2 gene produces two RNA transcript variants via alternative splicing which, in turn, encode distinct protein isoforms.;

GenBank Accession Number : NM_003075;

Details

Origin ID

C52053;

UMLS CUI

C1706263;

OMIM relation
- Swi/snf-related, matrix-associated, actin-dependent regulator of chromatin, subfamily C, member 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 12: 54869544-54843396 [NCIt concept]
gene_in_chromosomal_location
- 12q13-q14 [NCIt concept]
gene_is_element_in_pathway
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- IFN-Beta Enhancer Pathway [NCIt concept]
- hSWI-SNF Pathway [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients