EEF1D wt Allele

Preferred Label : EEF1D wt Allele;

NCIt synonyms : EF1D; Eukaryotic Translation Elongation Factor 1 Delta (Guanine Nucleotide Exchange Protein) wt Allele; FLJ20897; FP1047; EF-1D;

NCIt definition : Human EEF1D wild-type allele is located in the vicinity of 8q24.3 and is approximately 18 kb in length. This allele, which encodes elongation factor 1-delta protein, is involved in delivery of aminoacyl tRNAs to the ribosome during translation. The EEF1D gene is overexpressed in several types of cancer including esophageal carcinoma and hepatocellular carcinoma.;

NCIt note : The EEF1D gene produces three RNA transcript variants via alternative splicing which, in turn, encode distinct protein isoforms. Expression of this gene is induced by ionizing radiation.;

GenBank Accession Number : NM_001960;

Details

Origin ID

C52030;

UMLS CUI

C1707840;

OMIM relation
- Eukaryotic translation elongation factor 1, delta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_has_physical_location
- 8: 144750726-144733041 [NCIt concept]
gene_in_chromosomal_location
- 8q24.3 [NCIt concept]
gene_plays_role_in_process
- Protein Synthesis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients