NR0B2 wt Allele

Preferred Label : NR0B2 wt Allele;

NCIt synonyms : Nuclear Receptor Subfamily 0, Group B, Member 2 wt Allele; SHP1; SHP;

NCIt definition : Human NR0B2 wild-type allele is located in the vicinity of 1p36.1 and is approximately 2 kb in length. This allele, which encodes nuclear receptor 0B2 protein, is involved in transcriptional repression that is mediated by nuclear hormone receptor interactions. Mutations and dysfunction in the gene is associated with obesity.;

GenBank Accession Number : NM_021969;

Détails

Origin ID

C51707;

UMLS CUI

C1705299;

OMIM relation
- Nuclear receptor subfamily 0, group b, member 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Obesity [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1p36.1 [NCIt concept]
gene_is_element_in_pathway
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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