Breast Pleomorphic Carcinoma

Preferred Label : Breast Pleomorphic Carcinoma;

NCIt synonyms : Undifferentiated Breast Carcinoma; Anaplastic Breast Carcinoma; Pleomorphic Breast Carcinoma;

NCIt definition : A rare, aggressive, high grade invasive ductal carcinoma, not otherwise specified. It is characterized by the presence of pleomorphic and bizarre malignant cells that constitute more than 50 percent of the malignant cellular infiltrate.;

Neoplastic status : Malignant;

Details

Origin ID

C5161;

UMLS CUI

C1514169;

Currated CISMeF NLP mapping
- anaplastic breast carcinoma [Disease (Nov.)]
Disease excludes abnormal cell
- Malignant Squamous Cell [NCIt concept]
- Malignant Stromal Cell [NCIt concept]
- Neoplastic Smooth Muscle Cell [NCIt concept]
- Neoplastic Squamous Cell [NCIt concept]
Disease may have findings
- Breast Lump [NCIt concept]
- Calcification [NCIt concept]
- Pain [NCIt concept]
Has associated anatomic sites
- Breast [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- anaplastic breast carcinoma [Disease (Nov.)]
concept_is_in_subset
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Mixed Neoplastic Glandular and Squamous Cell Population [NCIt concept]
disease_excludes_molecular_abnormality
- CDH1 Gene Inactivation [NCIt concept]
- Loss of E-cadherin Expression [NCIt concept]
disease_has_abnormal_cell
- Adenocarcinoma Cell [NCIt concept]
- Ductal Carcinoma Cell [NCIt concept]
- Giant Adenocarcinoma Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Malignant Epithelial Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Neoplastic Glandular Cell [NCIt concept]
- Pleomorphic Adenocarcinoma Cell [NCIt concept]
disease_has_finding
- Carcinomatous Component Present [NCIt concept]
- Epithelial Component Present [NCIt concept]
- High Mitotic Activity [NCIt concept]
- Invasive Lesion [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Necrotic Change [NCIt concept]
- Not Otherwise Specified Lesion [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
disease_has_normal_cell_origin
- Epithelial Cell [NCIt concept]
- Terminal Ductal Lobular Unit Cell [NCIt concept]
disease_has_normal_tissue_origin
- Epithelial Tissue [NCIt concept]
- Mammary Epithelium [NCIt concept]
- Terminal Ductal Lobular Unit [NCIt concept]
disease_has_primary_anatomic_site
- Breast [NCIt concept]
disease_mapped_to_gene
- CCND1 Gene [NCIt concept]
- ERBB2 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Aneuploidy [NCIt concept]
disease_may_have_molecular_abnormality
- CCND1 Gene Amplification [NCIt concept]
- CCND1 Protein Overexpression [NCIt concept]
- Cyclin D1 Messenger RNA Overexpression [NCIt concept]
- ERBB2 Gene Amplification [NCIt concept]
- ERBB2 Protein Overexpression [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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