NCIt definition : Human NKTR wild-type allele is located within 3p23-p21 and is approximately 48 kb
in length. This allele, which encodes NK-tumor recognition protein, is involved in
the facilitation of natural killer cells and their binding targets.;
NCIt note : Human NKTR Gene at 3p23-p21 is involved in the recognition of tumor cells by the LGL
subpopulation of granular lymphocytes that kill tumor cells by an MHC-independent
mechanism. Alternative splicing occurs in the 5-prime region. Use of an alternate
exon 6 produces a truncated protein, while use of an alternate splice acceptor in
exon 9 generates a deletion.;