" /> PTN wt Allele - CISMeF





Preferred Label : PTN wt Allele;

NCIt synonyms : Pleiotrophin wt Allele; NEGF-1; NEGF1; HBNF; HARP; HBGF8; Pleiotrophin (Heparin Binding Growth Factor 8, Neurite Growth-Promoting Factor 1) Gene;

NCIt definition : Human PTN wild-type allele is located within 12p12.1-p11.2 and is approximately 14 kb in length. This allele, which encodes pleiotrophin protein, plays a role in mitogenesis for endothelial, epithelial, and fibroblast cells and neurite outgrowth. Further, aberrations of the gene result in allelic variants that are implicated in tumor invasion, angiogenesis, and metastasis.;

GenBank Accession Number : NM_002825;

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29/07/2025


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