CCKBR wt Allele

Preferred Label : CCKBR wt Allele;

NCIt synonyms : CCK-BR; Gastrin Receptor Gene; Cholecystokinin B Receptor wt Allele; CCK-B Receptor Gene; GASR; CCK2R; CCKRB;

NCIt definition : Human CCKBR wild-type allele is located in the vicinity of 11p15.4 and is approximately 12 kb in length. This allele, which encodes gastrin/cholecystokinin type B receptor protein, plays a role in modulating the regulatory peptides of the brain and gastrointestinal tract. A misspliced transcript allelic variant that includes an intron has been identified in cells from colorectal and pancreatic tumors.;

GenBank Accession Number : NM_176875;

Details

Origin ID

C51432;

UMLS CUI

C1707081;

Automatic exact mappings (from CISMeF team)
- Cholecystokinin b receptor [OMIM gene]
- receptor, cholecystokinin b [MeSH Descriptor]
OMIM relation
- Cholecystokinin b receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 6237542-6249932 [NCIt concept]
gene_in_chromosomal_location
- 11p15.4 [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Digestion [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Sensation [NCIt concept]
- Signal Transduction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]

Keyword's position in hierarchy(ies) :

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