ADRB1 wt Allele

Preferred Label : ADRB1 wt Allele;

NCIt synonyms : Adrenergic, Beta-1-, Receptor Gene; B1AR; BETA1AR; ADRB1R; RHR; Adrenoceptor Beta 1 wt Allele;

NCIt definition : Human ADRB1 wild-type allele is located within 10q24-q26 and is approximately 2 kb in length. This allele, which encodes beta-1 adrenergic receptor protein, is involved in the mediation of hormonal physiological effects from epinephrine and norepinephrine. Select polymorphisms of the gene have been shown to affect resting heart rate function and if dysregulated, can be involved in heart failure.;

GenBank Accession Number : NM_000684;

Details

Origin ID

C51429;

UMLS CUI

C1706649;

False automatic mappings
- Beta-1-adrenergic receptor [OMIM Phenotype]
OMIM relation
- Beta-1-adrenergic receptor [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 10: 115793796-115795518 [NCIt concept]
gene_in_chromosomal_location
- 10q24-q26 [NCIt concept]
gene_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
gene_plays_role_in_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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