IL2RB wt Allele

Preferred Label : IL2RB wt Allele;

NCIt synonyms : P70-75; Interleukin 2 Receptor, Beta wt Allele; CD122; IL15RB; Interleukin 15 Receptor, Beta Gene;

NCIt definition : Human IL2RB wild-type allele is located in the vicinity of 22q13.1 and is approximately 24 kb in length. This allele, which encodes interleukin-2 receptor subunit beta protein, is involved in T cell-mediated immune responses, receptor-mediated endocytosis and mitogenic signal transduction involving interleukin 2.;

GenBank Accession Number : NM_000878;

Details

Origin ID

C51363;

UMLS CUI

C1705799;

OMIM relation
- Interleukin 2 receptor, beta [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 22: 35870462-35846382 [NCIt concept]
gene_in_chromosomal_location
- 22q13.1 [NCIt concept]
gene_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
gene_plays_role_in_process
- Cell-Mediated Immunity [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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