IL2RA wt Allele

Preferred Label : IL2RA wt Allele;

NCIt synonyms : Interleukin 2 Receptor Subunit Alpha wt Allele; TCGFR; IL2R; CD25; IDDM10; IL2R, Alpha Chain Gene; Interleukin 2 Receptor, Alpha Gene; IMD41;

NCIt definition : Human IL2RA wild-type allele is located within 10p15-p14 and is approximately 51 kb in length. This allele, which encodes interleukin-2 receptor alpha chain protein, plays a role in clathrin-independent endocytosis, cytokine activation and immune functions.;

GenBank Accession Number : NM_000417;

Détails

Origin ID

C51362;

UMLS CUI

C1705979;

OMIM relation
- Interleukin 2 receptor, alpha [OMIM gene]
See also inter- (CISMeF)
- CD25 Ag [LOINC component]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 10: 6144278-6093512 [NCIt concept]
gene_in_chromosomal_location
- 10p15-p14 [NCIt concept]
gene_is_element_in_pathway
- Arf6 Trafficking Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL12-Mediated Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2-Mediated Signaling Pathway [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- IL2/STAT5 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- T-Cell Activation Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
gene_plays_role_in_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Immune System Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
genetic_biomarker_related_to
- CD25 Expression Measurement [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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