TK1 wt Allele - CISMeF

Preferred Label : TK1 wt Allele;

NCIt synonyms : Thymidine Kinase 1, Soluble wt Allele;

NCIt definition : Human TK1 wild-type allele is located within 17q23.2-q25.3 and is approximately 13 kb in length. This allele, which encodes thymidine kinase, cytosolic protein, plays a role in phosphorylation of thymidine to form deoxythymidine monophosphate. The TK1 gene is amplified in breast ductal carcinomas and overexpressed in other types of cancer such as colon cancer and thyroid carcinomas.;

GenBank Accession Number : NM_003258;

Details

Origin ID

C51329;

UMLS CUI

C1710299;

OMIM relation
- Thymidine kinase, soluble [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q23.2-q25.3 [NCIt concept]
gene_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Process [NCIt concept]
- Phosphorylation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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