ACKR4 wt Allele

Preferred Label : ACKR4 wt Allele;

NCIt synonyms : CCX CKR; C-C CKR-11; PPR1; Chemokine, C-C Motif, Receptor-Like Protein 1 Gene; C-C Chemokine Receptor Type 11 Gene; CCX-CKR; Chemokine (C-C Motif) Receptor-Like 1 Gene; Chemokine Receptor-Like 1 Gene; CC-CKR-11; CCR-11; VSHK1; CCBP2; PPR1, Bovine, Homolog of Gene; Atypical Chemokine Receptor 4 wt Allele; CKR-11; CCR10; CCRL1; CCR11; CCRL1 wt Allele;

NCIt definition : Human ACKR4 wild-type allele is located within 3q22 and is approximately 5 kb in length. This allele, which encodes atypical chemokine receptor 4 protein, plays a role in the mediation of activated chemokine binding.;

NCIt note : Predominant expression of 5.0, 2.0 and 1.3kb mRNA forms exist in human heart tissue, while low-level expression of the 2.0 and 1.3kb forms in lung, pancreas and spleen and in fetal tissues. The CCRL1 gene has one intron in the 5' untranslated region. Coupled transcription-translation of CCRL1 cDNA yielded a 45kD glycosylated protein. (OMIM);

GenBank Accession Number : NM_016557;

Details

Origin ID

C51327;

UMLS CUI

C1705083;

OMIM relation
- Atypical chemokine receptor 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 3: 133798792-133804080 [NCIt concept]
gene_in_chromosomal_location
- 3q22 [NCIt concept]
gene_plays_role_in_process
- Chemotactic Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Immunoregulation [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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