NCIt synonyms : P160ROCK; Rho-Associated, Coiled-Coil Containing Protein Kinase 1 Gene; Rho Associated Coiled-Coil Containing Protein Kinase 1 wt Allele; ROCK-I; Rho-Associated Coiled-Coil-Containing Protein Kinase 1 Gene;
NCIt definition : Human ROCK1 wild-type allele is located in the vicinity of 18q11.1 and is approximately
157 kb in length. This allele, which encodes Rho-associated protein kinase 1 protein,
plays a role in signal transduction, apoptotic membrane blebbing, exit from mitosis
and prevention of actin depolymerization.;
NCIt note : The ROCK1 gene is associated with the invasiveness of tumor cells.;