LYL1 wt Allele

Preferred Label : LYL1 wt Allele;

NCIt synonyms : LYL1 Basic Helix-Loop-Helix Family Member wt Allele; BHLHA18; Lymphoblastic Leukemia Derived Sequence 1 Gene; Lymphoblastic Leukemia Associated Hematopoiesis Regulator 1 Gene;

NCIt definition : Human LYL1 wild-type allele is located in the vicinity of 19p13.2 and is approximately 4 kb in length. This allele, which encodes Lyl-1 protein, is involved in hematopoiesis and transcriptional regulation. This gene is involved in T-cell acute lymphoblastic leukemia (T-ALL) through a chromosomal translocation t(7;9)(q35;p13), which involves LYL1 and T-cell receptor beta chain (TCRB) genes.;

GenBank Accession Number : NM_005583;

Details

Origin ID

C51280;

UMLS CUI

C1708629;

OMIM relation
- Lymphoblastic leukemia-derived sequence 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Acute Lymphoblastic Leukemia [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 19: 13074681-13070848 [NCIt concept]
gene_in_chromosomal_location
- 19p13.2 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients