RAF1 wt Allele

Preferred Label : RAF1 wt Allele;

NCIt synonyms : MIL; Mill Hill-2 Viral Oncogene Homolog; NS5; RAF-1; RAF; cRAF; c-Raf; Raf-1 Proto-Oncogene, Serine/Threonine Kinase wt Allele; CMD1NN; v-RAF-1 Murine Leukemia Viral Oncogene Homolog 1 Gene;

NCIt definition : Human RAF1 wild-type allele is located within 3p25 and is approximately 81 kb in length. This allele, which encodes RAF proto-oncogene serine/threonine-protein kinase protein, plays a role in the transduction of mitogenic signals from the cell membrane to the nucleus. Amplification of the RAF1 gene has been detected in certain cancers such as anaplastic large cell lymphomas, bladder carcinomas, nasopharyngeal carcinomas and hormone-resistant prostate cancer.;

GenBank Accession Number : NM_002880;

Details

Origin ID

C51274;

UMLS CUI

C1706586;

OMIM relation
- Raf1 protooncogene, serine/threonine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3p25 [NCIt concept]
gene_is_element_in_pathway
- Angiotensin II Signaling Pathway [NCIt concept]
- Aspirin Inhibition of Platelet Activation Pathway [NCIt concept]
- BCR Signaling Pathway [NCIt concept]
- Bioactive Peptide Signaling Pathway [NCIt concept]
- CCR3 Signaling Pathway [NCIt concept]
- CXCR4 Signaling Pathway [NCIt concept]
- Cadmium Induction Pathway [NCIt concept]
- Ceramide Signaling Pathway BioCarta [NCIt concept]
- EGF Signaling Pathway [NCIt concept]
- EPO Signaling Pathway [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Erk1/Erk2 MAPK Signaling Pathway [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway BioCarta [NCIt concept]
- Formyl Peptide Receptor 1 Signaling Pathway [NCIt concept]
- G-Protein Signaling Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- Growth Hormone Signaling Pathway [NCIt concept]
- Hepatocyte Growth Factor Receptor Signaling Pathway BioCarta [NCIt concept]
- IGF-1 Signaling Pathway [NCIt concept]
- IGF1R Antiapoptosis Pathway [NCIt concept]
- IL2 Signaling Pathway [NCIt concept]
- IL2RB Pathway [NCIt concept]
- IL3 Signaling Pathway [NCIt concept]
- IL6 Signaling Pathway [NCIt concept]
- Inhibition of Cellular Proliferation by Gleevec Pathway [NCIt concept]
- Insulin Signaling Pathway [NCIt concept]
- Integrin Signaling Pathway [NCIt concept]
- Keratinocyte Differentiation Pathway [NCIt concept]
- MAP Kinase Activation Pathway [NCIt concept]
- MAP Kinase Downregulation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- NFAT Pathway [NCIt concept]
- Nerve Growth Factor Pathway [NCIt concept]
- PDGF Signaling Pathway [NCIt concept]
- Pyk2 and Map Kinase Pathway [NCIt concept]
- Ras Signaling Pathway [NCIt concept]
- SRF Activation Pathway [NCIt concept]
- Sprouty Regulation of Tyrosine Kinase Signaling Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- TPO Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Cycle Regulation Process [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients