NCIt synonyms : Protein Kinase, cAMP-Dependent, Catalytic, Beta wt Allele;
NCIt definition : Human PRKACB wild-type allele is located in the vicinity of 1p36.1 and is approximately
160 kb in length. This allele, which encodes cAMP-dependent protein kinase, beta-catalytic
subunit protein, is involved in the phosphorylation of numerous cytoplasmic and nuclear
proteins in response to activation by the signaling molecule cyclic AMP.;
NCIt note : The PRKACB gene produces three alternatively-spliced transcript variants which encode
distinct isoforms of cAMP-dependent protein kinase, beta-catalytic subunit protein.;