" /> CTTN wt Allele - CISMeF





Preferred Label : CTTN wt Allele;

NCIt synonyms : Cortactin wt Allele; EMS1; Ems1 Sequence (Mammary Tumor and Squamous Cell Carcinoma-Associated (p80/85 Src Substrate) Gene; EMS1 wt Allele;

NCIt definition : Human CTTN wild-type allele is located within 11q13 and is approximately 38 kb in length. This allele, which encodes Src substrate cortactin protein, plays a role in regulating the interactions between components of adherens-type junctions and in organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. Aberrant regulation of this gene contributes to tumor cell invasion and metastasis, and it is overexpressed in breast cancer and squamous cell carcinomas of the head and neck.;

GenBank Accession Number : M98343;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
30/04/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.