NCIt definition : Human AKT1 wild-type allele is located in the vicinity of 14q32.32 and is approximately
26 kb in length. This allele, which encodes RAC-alpha serine/threonine-protein kinase
protein, plays a role in mediating the effects of various growth factors and is involved
in the transduction of anti-apoptotic and proliferation signals in T-cells. Inherited
defects in the AKT1 gene that result in deficiency of its protein product confer susceptibility
to schizophrenia.;