GRK2 wt Allele

Preferred Label : GRK2 wt Allele;

NCIt synonyms : BETA-ARK1; ADRBK1; Beta-ARK-1; BARK; BARK1; G Protein-Coupled Receptor Kinase 2 wt Allele; Adrenergic, Beta, Receptor Kinase 1 Gene; ADRBK1 wt Allele;

NCIt definition : Human GRK2 wild-type allele is located in the vicinity of 11q13.2 and is approximately 20 kb in length. This allele, which encodes beta-adrenergic receptor kinase 1 protein, is involved in the phosphorylation of beta-adrenergic and related G protein-coupled receptors.;

GenBank Accession Number : NM_001619;

Details

Origin ID

C51179;

UMLS CUI

C1705403;

OMIM relation
- G protein-coupled receptor kinase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 11: 66790663-66810945 [NCIt concept]
gene_in_chromosomal_location
- 11q13.2 [NCIt concept]
gene_is_element_in_pathway
- Chemokine Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- GPCR Desensitization Pathway [NCIt concept]
- GPCR Signaling Pathway [NCIt concept]
- HDAC Class II Signaling Pathway [NCIt concept]
- MAP Kinase Activation Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients