RYK wt Allele - CISMeF

Preferred Label : RYK wt Allele;

NCIt synonyms : D3S3195; RYK Receptor-Like Tyrosine Kinase wt Allele; RYK1;

NCIt definition : Human RYK wild-type allele is located within 3q22 and is approximately 94 kb in length. This allele, which encodes tyrosine-protein kinase RYK protein, plays a role in Wnt-mediated signaling which regulates developmental processes such as cell proliferation, differentiation and epithelial-mesenchymal interactions. The RYK gene is overexpressed in epithelial ovarian cancer.;

NCIt note : The RYK gene undergoes alternative splicing to yield two RNA transcript variants, which encode distinct isoforms of the tyrosine-protein kinase RYK protein.;

GenBank Accession Number : NM_002958;

Details

Origin ID

C51177;

UMLS CUI

C1706617;

OMIM relation
- Ryk receptor-like tyrosine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q22 [NCIt concept]
gene_plays_role_in_process
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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