RPS6KB2 wt Allele

Preferred Label : RPS6KB2 wt Allele;

NCIt synonyms : Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 wt Allele; P70-BETA; p70S6Kb;

NCIt definition : Human RPS6KB2 wild-type allele is located in the vicinity of 11q13.1 and is approximately 7 kb in length. This allele, which encodes ribosomal protein S6 kinase 2 protein, plays a role in protein synthesis via the phosphorylation of ribosomal protein 6. The RPS6KB2 gene is overexpressed in certain cancers such as adenocarcinomas of the breast and endometrium.;

NCIt note : The RPS6KB2 gene undergoes alternative splicing to yield two transcript variants and two corresponding isoforms of ribosomal protein S6 kinase 2 protein.;

GenBank Accession Number : NM_003952;

Details

Origin ID

C51175;

UMLS CUI

C1705800;

OMIM relation
- Ribosomal protein s6 kinase b2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q13.1 [NCIt concept]
gene_is_element_in_pathway
- Acute Myeloid Leukemia Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- MAPKinase Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_plays_role_in_process
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients