ITGAL wt Allele

Preferred Label : ITGAL wt Allele;

NCIt synonyms : LFA-1; Integrin Subunit Alpha L wt Allele; LFA1A; CD11A; Integrin, Alpha-L Gene; Integrin, Alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; Alpha Polypeptide) Gene; Lymphocyte Function-Associated Antigen, Type 1, Alpha Subunit Gene;

NCIt definition : Human ITGAL wild-type allele is located in the vicinity of 16p11.2 and is approximately 50 kb in length. This allele, which encodes integrin alpha-L protein, plays a role in leukocyte intercellular adhesion and lymphocyte costimulatory signal transduction.;

GenBank Accession Number : NM_002209;

Details

Origin ID

C51165;

UMLS CUI

C1706332;

OMIM relation
- Integrin, alpha-L [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 16: 30391572-30442007 [NCIt concept]
gene_in_chromosomal_location
- 16p11.2 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- CTL-mediated Immune Response Pathway [NCIt concept]
- CXCR3-Mediated Signaling Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- Local Acute Inflammatory Response Pathway [NCIt concept]
- Lymphocyte Adhesion Pathway [NCIt concept]
- Malaria Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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