" /> FRK wt Allele - CISMeF





Preferred Label : FRK wt Allele;

NCIt synonyms : RAK; GTK; PTK5; Fyn Related Src Family Tyrosine Kinase wt Allele; GTK, Mouse, Homolog of Gene; Fyn-Related Src Family Tyrosine Kinase Gene; PTK5 Protein Tyrosine Kinase 5 Gene; FYN-Related Kinase Gene;

NCIt definition : Human FRK wild-type allele is located within 6q21-q22.3 and is approximately 119 kb in length. This allele, which encodes tyrosine-protein kinase FRK protein, plays a role in cell cycle inhibition at the G1/S checkpoint and negative regulation of cell growth putatively via phosphorylation of perinuclear proteins.;

NCIt note : Tyrosine-protein kinase FRK protein blocks the proliferation of breast cancer cell lines.;

GenBank Accession Number : NM_002031;

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31/07/2025


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