" /> MPP1 wt Allele - CISMeF





Preferred Label : MPP1 wt Allele;

NCIt synonyms : EMP55; DXS552E; DXS552; PEMP; Membrane Protein, Palmitoylated 1 (55kD) Gene; MRG1; Membrane Protein, Palmitoylated 1 Gene; Membrane Protein, Palmitoylated 1, 55kDa Gene; Aging-Associated Gene 12; AAG12; Membrane Palmitoylated Protein 1 wt Allele; Migration-Related Gene 1;

NCIt definition : Human MPP1 wild-type allele is located within Xq28 and is approximately 27 kb in length. This allele, which encodes 55 kDa erythrocyte membrane protein, is involved in coupling the cytoskeleton to the erythrocyte cell membrane and plays a putative role in signal transduction.;

NCIt note : The MPP1 gene is overexpressed in lung adenocarcinomas carrying mutations in the LKB1 tumor suppressor gene. MPP1 is a candidate gene for cross-resistance against DNA-damaging chemotherapeutic drugs.;

GenBank Accession Number : NM_002436;

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20/05/2024


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