" /> SIRPA wt Allele - CISMeF





Preferred Label : SIRPA wt Allele;

NCIt synonyms : SIRPalpha2; BIT; Macrophage Fusion Receptor Gene; P84; SIRP-ALPHA-1; PTPNS1; SHPS1; SIRP; MFR; SIRPalpha Variant 1 Allele; SIRPalpha; MYD-1; Signal-Regulatory Protein Alpha Gene; CD172A; Protein-Tyrosine Phosphatase, Nonreceptor Type, Substrate 1 Gene; Protein Tyrosine Phosphatase, Non-Receptor Type Substrate 1 Gene; PTPNS1 wt Allele; Signal Regulatory Protein, Alpha Type, 1 Gene; MYD1; SIRPA V1 Allele; SIRPalpha V1 Allele; SIRPA Variant 1 Allele; Signal Regulatory Protein-Alpha V1 Allele; Signal Regulatory Protein Alpha wt Allele; Signal Regulatory Protein Alpha V1 Allele;

NCIt definition : Human SIRPA wild-type allele is located within 20p13 and is approximately 45 kb in length. This allele, which encodes tyrosine-protein phosphatase non-receptor type substrate 1 protein, is involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes.;

NCIt note : This gene encodes a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Members of the SIRP family and related genes are located in close proximity to each other on chromosome 20p13.;

GenBank Accession Number : NM_080792;

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30/05/2025


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