XRCC4 wt Allele

Preferred Label : XRCC4 wt Allele;

NCIt synonyms : X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 4 wt Allele; X-Ray Repair, Complementing Defective, in Chinese Hamster, 4 Gene;

NCIt definition : Human XRCC4 wild-type allele is located within 5q13-q14 and is approximately 276 kb in length. This allele, which encodes DNA-repair protein XRCC4, plays a role in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.;

NCIt note : The XRCC4 gene contains 8 exons, and alternative transcription initiation and alternative splicing generates several transcript variants and two protein isoforms.;

GenBank Accession Number : NM_003401;

Details

Origin ID

C51015;

UMLS CUI

C1710691;

OMIM relation
- X-ray repair cross complementing 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5q13-q14 [NCIt concept]
gene_is_element_in_pathway
- Non-Homologous End-Joining Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Repair [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Nonhomologous DNA End Joining [NCIt concept]
- V(D)J Recombination [NCIt concept]

Keyword's position in hierarchy(ies) :

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