TOPBP1 wt Allele

Preferred Label : TOPBP1 wt Allele;

NCIt synonyms : TOP2BP1; Topoisomerase (DNA) II Binding Protein Gene; Hypothetical Protein KIAA0259 Gene; DNA Topoisomerase II Binding Protein Gene; KIAA0259; Topoisomerase (DNA) II Binding Protein 1 wt Allele;

NCIt definition : Human TOPBP1 wild-type allele is located in the vicinity of 3q22.1 and is approximately 61 kb in length. This allele, which encodes DNA topoisomerase 2-binding protein 1, is involved in DNA double-strand breaks, and map play a role in DNA damage and replication checkpoint controls.;

GenBank Accession Number : NM_007027;

Details

Origin ID

C51008;

UMLS CUI

C1710311;

Automatic exact mappings (from CISMeF team)
- Dna topoisomerase II-binding protein 1 [OMIM gene]
OMIM relation
- Dna topoisomerase II-binding protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 3q22.1 [NCIt concept]
gene_is_element_in_pathway
- BARD1 Signaling Pathway [NCIt concept]
- E2F Transcription Factor Pathway [NCIt concept]
gene_plays_role_in_process
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]

Keyword's position in hierarchy(ies) :

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