Refractory Splenic Marginal Zone Lymphoma

Preferred Label : Refractory Splenic Marginal Zone Lymphoma;

NCIt synonyms : Refractory Splenic Marginal Zone B-Cell Lymphoma;

NCIt definition : Splenic marginal zone lymphoma that is resistant to treatment.;

Neoplastic status : Malignant;

Details

Origin ID

C5096;

UMLS CUI

C0856023;

Currated CISMeF NLP mapping
- Splenic marginal zone lymphoma refractory [MedDRA Preferred Term]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Monoclonal Gammopathy [NCIt concept]
- Peripheral Blood Involvement [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- Splenic marginal zone lymphoma refractory [MedDRA Preferred Term]
disease_excludes_finding
- Aggressive Clinical Course [NCIt concept]
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Small to Medium-Sized B-Lymphocyte with Pale Cytoplasm [NCIt concept]
disease_has_finding
- Malignant Cellular Infiltrate [NCIt concept]
- Refractory Disease [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_molecular_abnormality
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Heavy Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Kappa Light Chain Gene Rearrangement [NCIt concept]
- Clonal Immunoglobulin Lambda Light Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Marginal Zone B-Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Postgerminal Center B-Lymphocyte of Unknown Differentiation Stage [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
- Marginal Zone [NCIt concept]
- Splenic Marginal Zone [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
disease_may_have_abnormal_cell
- Neoplastic Plasma Cell [NCIt concept]
- Villous Lymphocyte [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Hepatitis C Infection [NCIt concept]
- Thrombocytopenia Due to Immune Destruction [NCIt concept]
disease_may_have_cytogenetic_abnormality
- del(7q21-32) [NCIt concept]
disease_may_have_molecular_abnormality
- KLF2 Gene Mutation [NCIt concept]
- KMT2D Gene Mutation [NCIt concept]
- NOTCH2 Gene Mutation [NCIt concept]
- TNFAIP3 Gene Mutation [NCIt concept]
- TP53 Gene Mutation [NCIt concept]

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