NDOR1 wt Allele

Preferred Label : NDOR1 wt Allele;

NCIt synonyms : NR1; NADPH Dependent Diflavin Oxidoreductase 1 wt Allele; NR1 wt Allele;

NCIt definition : Human NDOR1 wild-type allele is located in the vicinity of 9q34.3 and is approximately 11 kb in length. This allele, which encodes NADPH-dependent FMN-and FAD-containing oxidoreductase protein, is putatively involved in the metabolic activation of chemicals, such as anticancer drugs, via one-electron reduction.;

NCIt note : The NDOR1 gene exhibits significant sequence similarities with both the POR gene and NOS1 gene. An allelic variant of the NDOR1 gene has been identified which yields a protein product with very low enzymatic activity.;

GenBank Accession Number : NM_014434;

Details

Origin ID

C50902;

UMLS CUI

C1706269;

OMIM relation
- Nadph-dependent diflavin oxidoreductase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 9q34.3 [NCIt concept]
gene_plays_role_in_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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