NCIt definition : Corneal edema of inflammatory origin associated with contact lens wear and morphologically
characterized by presence of epithelial microcysts. Microcysts are small (typically
10-50 microns in diameter), clear, irregularly shaped high refractive inclusions that
form in the basal layers of the epithelium and move towards the anterior surface of
the cornea, surrounding epithelial haze. The cause of microcytic edema is related
to the physical presence of contact lenses and possibly a mechanical effect of lens
wear.;
Alternative definition : FDA: Corneal edema of inflammatory origin associated with contact lens wear and morphologically
characterized by presence of epithelial microcysts.;