" /> LOX wt Allele - CISMeF





Preferred Label : LOX wt Allele;

NCIt synonyms : Lysyl Oxidase wt Allele;

NCIt definition : Human LOX wild-type allele is located in the vicinity of 5q23.2 and is approximately 12 kb in length. This allele, which encodes protein-lysine 6-oxidase protein, is involved in initiating the cross-linking of collagens and elastin. LOX gene expression is associated with both metastasis and poor patient survival in several types of cancer including breast and head and neck cancers.;

NCIt note : LOX gene expression is essential for hypoxia-induced metastasis.;

GenBank Accession Number : NM_002317;

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12/05/2024


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