" /> DHODH wt Allele - CISMeF





Preferred Label : DHODH wt Allele;

NCIt synonyms : Dihydroorotate Dehydrogenase wt Allele;

NCIt definition : Human DHODH wild-type allele is located within 16q22 and is approximately 16 kb in length. This allele, which encodes dihydroorotate dehydrogenase, mitochondrial protein, is involved in de novo pyrimidine biosynthesis.;

NCIt note : Dihydroorotate dehydrogenase is a drug target in the pyrimidine biosynthetic pathway. Mutations in the DHODH gene that affect the expression or catalytic activity of this enzyme may alter the efficacy of chemotherapy.;

GenBank Accession Number : NM_001361;

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20/05/2024


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