ALOX15 wt Allele

Preferred Label : ALOX15 wt Allele;

NCIt synonyms : LOG15 Gene; Arachidonate 15-Lipoxygenase wt Allele;

NCIt definition : Human ALOX15 wild-type allele is located in the vicinity of 17p13.3 and is approximately 11 kb in length. This allele, which encodes arachidonate 15-lipoxygenase protein, plays a role in leukotriene biosynthesis. Decreased expression of the ALOX 15 gene is associated with several types of cancer including breast and colorectal cancer.;

GenBank Accession Number : NM_001140;

Details

Origin ID

C50814;

UMLS CUI

C1706660;

OMIM relation
- Arachidonate 15-lipoxygenase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 17: 4491709-4480965 [NCIt concept]
gene_in_chromosomal_location
- 17p13.3 [NCIt concept]
gene_is_element_in_pathway
- IL4-Mediated Signaling Pathway [NCIt concept]
- Linoleic Acid Metabolism Pathway [NCIt concept]
- Prostaglandin and Leukotriene Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Biosynthetic Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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