Preferred Label : Fluoxymesterone;
NCIt synonyms : Androfluorene; Androsterolo; (11Beta,17beta)-9-fluoro-11,17-dihydroxy-17-methylandrost-4-en-3-one; 9Alpha-fluoro-11beta-hydroxy-17alpha-methyltestosterone; FXM; 11Beta,17beta-dihydroxy-9alpha-fluoro-17alpha-methyl-4-androsten-3-one;
NCIt related terms : Ora-testryl; Halotestin; Ora Testryl; Oratestin; Ultandren; Testoral;
NCIt definition : A halogenated derivative of 17-alpha-methyltestosterone. Similar to testosterone,
fluoxymesterone binds to and activates specific nuclear receptors, resulting in an
increase in protein anabolism, a decrease in amino acid catabolism, and retention
of nitrogen, potassium, and phosphorus. This agent also may competitively inhibit
prolactin receptors and estrogen receptors, thereby inhibiting the growth of hormone-dependent
tumor lines. Fluoxymesterone is approximately five times more potent than methyltestosterone.
(NCI04);
UNII : 9JU12S4YFY;
InChIKey : YLRFCQOZQXIBAB-RBZZARIASA-N;
CAS number : 76-43-7;
Drug name : Oratestin; Stenox; Ultandren; Halotestin; Halodrin; Ora-Testryl; Testoral; Android-F; Androxy;
Chemical formula : C20H29FO3;
NSC code : 12165;
ChEBI ID : CHEBI:5120;
Codes from synonyms : NSC0012165; 226;
Origin ID : C507;
UMLS CUI : C0016366;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- Validated automatic mappings to BTNT
- concept_is_in_subset
- is_component_of_chemotherapy_regimen
