Corneal Decompensation

Preferred Label : Corneal Decompensation;

NCIt synonyms : Corneal Endothelial Decompensation;

NCIt definition : Endothelial decompensation that is manifested by opacity of the cornea. The condition often occurs as a nonspecific response to mechanical injury from incidental corneal contact by intraocular instruments during surgery; chemical injury from the improper use of intraocular drugs, drugs containing preservatives, or from residues from inadequate rinsing of detergents or other residues from surgical instruments. The most common causes of corneal endothelial decompensation in the adult population are cataract removal/IOL-related endothelial loss and Fuchs dystrophy. When severe, corneal endothelial decompensation requires corneal transplantation.;

Alternative definition : FDA: Inability to maintain corneal integrity; or corneal edema resulting from failure of the corneal endothelium to maintain detumescence.;

FDA table : Patient Code (Appendix B);

Codes from synonyms : 1790;

Details

Origin ID

C50507;

UMLS CUI

C0948284;

Automatic exact mappings (from CISMeF team)
- Corneal decompensation (disorder) [SNOMED CT concept]
Currated CISMeF NLP mapping
- Corneal decompensation [MedDRA Preferred Term]
Has associated anatomic sites
- Cornea [NCIt concept]
- Eye [NCIt concept]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Corneal decompensation [MedDRA Preferred Term]
- Corneal decompensation (disorder) [SNOMED CT concept]
concept_is_in_subset
- CDRH Health Effects - Clinical Signs and Symptoms or Conditions Terminology [NCIt concept]
- FDA Center For Devices and Radiological Health Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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