ST14 wt Allele

Preferred Label : ST14 wt Allele;

NCIt synonyms : TMPRSS14; PRSS14; MTSP-1; MTSP1; MT-SP1; HAI; TADG-15; SNC19; TADG15; ARCI11; Suppression of Tumorigenicity 14 (Colon Carcinoma, Matriptase, Epithin) Gene; CAP3; ST14 Transmembrane Serine Protease Matriptase wt Allele; Suppression Of Tumorigenicity 14 (Colon Carcinoma) Gene; Tumor Associated Differentially Expressed Gene 15;

NCIt definition : Human ST14 wild-type allele is located within 11q24-q25 and is approximately 51 kb in length. This allele, which encodes suppressor of tumorigenicity 14 protein, is involved in the cleavage/activation of other proteases and latent growth factors. Decreased expression of the ST14 gene is associated with tumor metastasis.;

GenBank Accession Number : NM_021978;

Details

Origin ID

C50376;

UMLS CUI

C1704882;

Automatic exact mappings (from CISMeF team)
- Ichthyosis, congenital, autosomal recessive 11 [OMIM Phenotype]
- Protease inhibitor 9, ovalbumin type [OMIM gene]
- ST14 transmembrane serine protease matriptase [ORDO Gene]
- Serine peptidase inhibitor, kunitz-type, 1 [OMIM gene]
- St14 transmembrane serine protease matriptase [OMIM gene]
- cross infection [MeSH Descriptor]
- viral hemagglutination inhibition assay [OBI concept]
OMIM relation
- St14 transmembrane serine protease matriptase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 11q24-q25 [NCIt concept]
gene_plays_role_in_process
- Hydrolysis [NCIt concept]
- Post-Translational Regulation [NCIt concept]
- Proteolysis [NCIt concept]

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